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OCR: enance usually For chronic adrenocortical failure, mai therapy with hydrocortisone is initiate ce the together with 9x-fludrocortisone to rep mineralocorticoid deficiency. rtisone on Most patients require 20mg oral hydro ents feel waking and 10mg at 1800. Occasional p es daily better on hydrocortisone given three ti ment rather than twice daily. Adequate repla but Plasma therapy should reverse the pigmentati should not produce Cushing's syndror g the day cortisol levels should be measured dur he correct on replacement therapy to determine i dose has been given (Fig. 9.11). See later: · Mineralocorticoid Replacement